Prostaglandin E2 Suppresses Lipopolysaccharide-Stimulated IFN-β Production
نویسندگان
چکیده
منابع مشابه
Inhibition of MAP kinase kinase prevents cytokine and prostaglandin E2 production in lipopolysaccharide-stimulated monocytes.
Activation of the extracellular signal-regulated kinase (ERK) pathway has been shown to occur in monocytes following stimulation with LPS. However, the importance of this event for monocyte function is not clear. To address this issue, we used the novel MAP/ERK kinase (MEK) inhibitor, U0126. Stimulation of monocytes with LPS resulted in activation of the mitogen-activated protein kinase (MAPK) ...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2008
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.180.4.2125